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By finding recombination frequencies for many gene pairs, we can make linkage maps that show the order and relative distances of the genes on the chromosome.
Genetic mapping is a way to identify exactly which chromosome has which gene and exactly pinpointing where that gene lies on that particular chromosome. Mapping also acts as a method in determining which gene is most likely to recombine based on the distance between two genes.
A genetic map indicates the relative distance between genes or markers, represented by the recombination value and measured in cM. A physical map highlights the physical distance between genes or markers, the distance unit is a length unit, such as micrometers (μm) or base pair numbers (bp or kp).
Calculate the map distance between loci given the phenotypes of offspring or predict phenotypes of offspring given the recombination frequency between loci. Use the distance to construct genetic maps based on data from two-point or three-point testcrosses.
A genetic map shows the map distance, in cM, that separates any two loci, and the position of these loci relative to all other mapped loci. The genetic map distance is roughly proportional to the physical distance, i.e., the amount of DNA between two loci.
A genetic map (or recombination map) is a representation of the linear order of genes (or loci), and their relative distances determined by crossover frequency, along a chromosome. The fact that such linear maps can be constructed supports the concept of genes being arranged in a fixed, linear order along a single duplex of DNA for each chromosome.
It is possible to determine the approximate distance between genetic markers using cytogenetic mapping, but not the exact distance (number of base pairs). Radiation hybrid mapping uses radiation, such as x-rays, to break the DNA into fragments.
