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4 maj 2024 · The proposed method predicts distance maps with a mean absolute error ( MAE) of 2.32Å and a root mean squared error ( RMSE) of 3.63Å on novel proteins. It predicts residue–residue distances more accurately than state-of-the-art structure prediction methods (ESMFold) with 3.74‰ inference time of it.
By finding recombination frequencies for many gene pairs, we can make linkage maps that show the order and relative distances of the genes on the chromosome.
10 sty 2022 · The development of pE-MAP and DMS enabled the systematic study of the relationship between genetic interactions and residue distances in a protein structure.
Explain why a map is an important aid to genome sequencing. Distinguish between the terms ‘genetic map’ and ‘physical map’. Describe the different types of marker used to construct genetic maps, and state how each type of marker is scored.
6 kwi 2022 · Writing in Nature, Faure et al. 1 report the first integrated method to globally map, quantify and distinguish the effects of mutations on allostery and protein stability. Their approach is...
4 maj 2024 · The results demonstrate that FreeProtMap significantly outperforms other state-of-the-art methods in accurate protein residue-residue distance prediction, which is beneficial for lots of protein research works.
29 wrz 2020 · The ability to infer a complete genotype-phenotype map from a small dataset of experimentally determined phenotypes would therefore be extremely useful to a broad range of biology researchers. In this study, we sought to infer phenotypes in a map of intermediate size, containing 2 8 = 256 genotypes.
