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By finding recombination frequencies for many gene pairs, we can make linkage maps that show the order and relative distances of the genes on the chromosome.
Design a series of crosses to determine the map distance between these two loci. You can start with any genotypes you want, but be sure to specify the phenotypes of individuals at each stage of the process.
gene for antenna length is 5% (i.e. the genetic distance between them is 5 centimorgans). List all possible recombination frequencies between the gene for color and the gene for antenna length.
• Mapping reveals the relative order of genes, not the actual physical distance. • The most accurate maps are made by summing the genetic distances of genes lying close together (small intervals). One needs to connect genes that lie far apart through the genes that lie between them.
Calculate the map distance between loci given the phenotypes of offspring or predict phenotypes of offspring given the recombination frequency between loci. Use the distance to construct genetic maps based on data from two-point or three-point testcrosses.
To understand the linear arrangement of genes along a chromosome. To understand how meiosis and crossing over results in recombinant gametes. To predict the outcome of genetic crosses involving one, two or three linked genes. To draw a simple genetic map based upon data from test crosses.
Recombination frequency and gene mapping. Genes A, B, G, and H are located on the same chromosome. The distances between the genes are below:
