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On a set of 42 bacterial genomes of different sizes, and with reasonably separated evolutionary trajectories, we investigate three issues: i) whether the distribution of connectivities changes between PPI subnetworks of essential and nonessential genes; ii) how gene conservation, measured both by the evolutionary retention index (ERI) and by ...
10 sie 2015 · Fuelled by a number of genetic, biochemical and fluorescence-based techniques, our ability to map bacterial protein networks and to investigate their functions has increased dramatically in...
11 lis 2009 · Bacteria deploy proteins and protein complexes to particular locations and do so in a dynamic manner in lockstep with the organized deployment of their chromosome. The dynamic subcellular localization of protein complexes is an integral feature of regulatory processes of bacterial cells.
24 wrz 2008 · The 419 multiprotein operons contained 1,319 proteins. The intergenic distances between predicted protein linkage pairs by the Gene cluster method for E. coli K12 and B. subtilis were calculated using the NCBI annotations . We evaluated the GC predicted linkages using Precision and Recall measures.
These two principles lead to a quantitative formulation of the central dogma of bacterial gene expression, connecting mRNA and protein concentrations to the regulatory activities of the corresponding promoters.
Key Points. In recent years, bacterial cells have been shown to be spatially organized by localized protein complexes and dynamic cytoskeletal filaments. Localized protein complexes are...
11 lip 2018 · Bacterial RNA-binding proteins (RBPs) directly associate with and influence the fate of virtually all cellular transcripts. In this Review, Holmqvist and Vogel discuss our current...
