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By finding recombination frequencies for many gene pairs, we can make linkage maps that show the order and relative distances of the genes on the chromosome.
20 godz. temu · July 23, 2019 — UC San Diego researchers have used the transcriptome -- the sum of all messenger RNA (mRNA) molecules expressed from genes -- to map protein-gene interactions involved in ...
10 sty 2022 · To achieve a systems view, protein interaction networks map which proteins physically interact, while genetic interaction networks inform on the phenotypic consequences of perturbing these...
11 sty 2018 · Chemical proteomics provides a map of metabolite-protein interactions • Metabolite binding sites pinpointed on a proteome-wide scale • New catalytic, allosteric, and metabolite-induced protein-protein interaction events • Binding of metabolites at binding sites is promiscuous
8 cze 2007 · In vivo protein-DNA interactions connect each transcription factor with its direct targets to form a gene network scaffold. To map these protein-DNA interactions comprehensively across entire mammalian genomes, we developed a large-scale chromatin immunoprecipitation assay (ChIPSeq) based on direct ultrahigh-throughput DNA sequencing.
1 sty 1985 · Rao and Rossmann 23 were the first proponents of distance maps as a systematical way of locating domains in lactate dehy- drogenase and flavodoxin, while Ooi and Nishikawa 22 applied it to a- chymotrypsin and myoglobin, and Rossmann and Liljas 24 to a large sam- ple of other proteins.
6 kwi 2022 · A general method that quantifies and disentangles the effects of a gene’s mutations on the traits of its protein enables assessments of mutational effects on protein biophysics for many of...
