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The Geographic Distance Matrix Generator is a platform-independent Java application that implements the same powerful suite of spherical functions as the Perpendicular Distance Calculator to compute all pair wise distances from a simple list of geographic coordinates.
This section focuses first on how we estimate distances, depending upon the level of interest, and then highlights some approaches for visualizing and gaining inferences from the distance matrix itself.
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In our framework, we have designed two strategies to accelerate the computation based on 1) cell graph coarse-graining, and 2) gene graph sparsification. Briefly, cell graph coarse-graining aims to reduce the cell number by aggregating nearest cells into “meta-cells”.
The distance matrix is widely used in the bioinformatics field, and it is present in several methods, algorithms and programs. Distance matrices are used to represent protein structures in a coordinate-independent manner, as well as the pairwise distances between two sequences in sequence space.
11 mar 2020 · The genodive GUI also makes it easy to import and export distance matrices from and to other programs. For importing triangular matrices, genodive has a smart algorithm to detect whether it is a lower or upper diagonal matrix, based on triangle inequality.