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28 lut 2018 · The Z line demarcates the squamocolumnar junction (SCJ), the transition from the squamous esophageal mucosa to the columnar mucosa lining the stomach, or in cases of Barrett’s esophagus, between the squamous and intestinalized columnar epithelium of the metaplastic segment.
Since gastroesophageal reflux is known to be of etiological importance in both Barrett's esophagus and esophageal adenocarcinoma, we aimed to study which endoscopic alterations at the Z-line can be attributed to a previous history of reflux symptoms.
Should We Biopsy an Irregular Z-Line? The Yield of Biopsy to Diagnose Short-Segment Barrett's Esophagus. Background: The diagnosis of Barrett's esophagus (BE) requires the demonstration of specialized intestinal metaplasia (SIM) within the tubular esophagus.
Screening for BE currently includes patients with risk factors for the disease undergoing an endoscopic evaluation with esophagoduodenoscopy (EGD) or transnasal endoscopy (TNE). Esophageal biopsies are performed if the endoscopic appearance of the distal esophagus is consistent with BE with the presence of at least 1 cm of columnar-appearing ...
ZAP (Z-line appearance) classification evaluates the endo- scopic appearance of the Z-line, and it has been associated both with the prevalence of IM, as well as with GER [11–13].
8 sie 2022 · At the time of EGD, the esophageal landmarks are noted: diaphragmatic pinch at 40 cm, top of the gastric folds at 40 cm, and an irregular Z line at 40 cm (Figure 1). The remainder of the EGD was unremarkable.
23 maj 2021 · Barrett’s esophagus (BE) is a known risk factor for esophageal adenocarcinoma (EAC) and consensus guidelines recommend a standardized approach to endoscopic screening and surveillance. Segments less than one centimeter are often described as an irregular Z line.
