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10 sie 2015 · In this Review, we present our current understanding of bacterial protein networks, their general properties and the tools that are used for systematically mapping and characterizing them.
By finding recombination frequencies for many gene pairs, we can make linkage maps that show the order and relative distances of the genes on the chromosome.
Recombination frequencies can be used to determine the distances between genes and their order on the phage chromosome, just as they are used to map genes in eukaryotes.
On a set of 42 bacterial genomes of different sizes, and with reasonably separated evolutionary trajectories, we investigate three issues: i) whether the distribution of connectivities changes between PPI subnetworks of essential and nonessential genes; ii) how gene conservation, measured both by the evolutionary retention index (ERI) and by ...
11 lis 2009 · In one bacterial species, Caulobacter crescentus, at least 10% of predicted encoded proteins exhibited specific subcellular organization . Here, we explore why bacteria dynamically deploy key regulatory proteins to particular sites in the cell and how this positioning and repositioning is achieved.
Genetic information in bacteria and many viruses is encoded in DNA, but some viruses use RNA. Replication of the genome is essential for inheritance of genetically determined traits. Gene expression usually involves transcription of DNA into messenger RNA and translation of mRNA into protein.
17 lis 2011 · Unbiased genetic screens can reveal unexpected functional dependencies between genetic loci (i.e. epistasis, wherein the phenotypic effects of mutation of one gene are modified by one or more other genes).
