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4 dni temu · ezSingleCell is an interactive and easy-to-use application for analysing various single-cell and spatial omics data types without requiring prior programing knowledge. It combines the best ...
3 dni temu · We noticed that the association signals for known genes were generally higher than those of novel genes (P = 1.25 × 10 −12, two-sided Student’s t-test), with average −logP signals of 44.7 and 20.8, respectively. This is presumably because major effect genes are more easily characterized by map-based cloning.
6 dni temu · The percent recombination between two linked genes can be directly converted into units of genetic distance called centi- Morgans or map units. While these genetic distances are only estimates of the true physical distance between two genes, they are still extremely valuable, as we will discuss in the Applications portion of the web site.
5 dni temu · Tumor Microenvironment: In cancer research, understanding how immune cells and tumor cells interact at the molecular level is crucial for developing new therapies. Applications in Research. Spatial Transcriptomics: This method maps gene expression across different tissues, revealing how individual cells and cell clusters communicate. It ...
4 dni temu · A genetic map (also called a linkage map) shows the relative location of genetic markers (reflecting sites of genomic variants) on a chromosome. A genetic map is based on the concept of genetic linkage: the closer two markers are to each other on a chromosome, the greater the probability that they will be inherited together.
5 dni temu · Certain epigenetic modifications may be passed on from parent cell to daughter cell during cell division or from one generation to the next. The collection of all epigenetic changes in a genome is called an epigenome.
4 dni temu · Linkage, as related to genetics and genomics, refers to the closeness of genes or other DNA sequences to one another on the same chromosome. The closer two genes or sequences are to each other on a chromosome, the greater the probability that they will be inherited together.
