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4 dni temu · These maps require structural data, such as the 3D configuration and positioning of tissues and cells, and molecular data on the constitution of each cell, spanning from the DNA sequence to ...
1 dzień temu · The metadata in the Allen Brain Cell Atlas, though, seems to use a parcellation index rather than the anatomical ontology IDs used in other datasets. For example, the “Entorhinal area, lateral part, layer 1” has a parcellation index of 1109.
5 dni temu · The liver has the remarkable ability to regenerate. Applying single-cell transcriptomics and iterative immunofluorescence imaging on patient-derived samples, this study revealed cellular gene ...
5 dni temu · Figure 1: Overview of the proposed DeepCMorph network architecture. The model consists of two separate modules: the first one performs nuclei segmentation and cell type annotation. Its outputs are then stacked together with the original histopathology image and are passed to the second module performing the final classification task.
4 dni temu · Mapping refers to the process of determining the relative locations of landmarks or markers (such as genes, variants and other DNA sequences of interest) within a chromosome or genome.
5 dni temu · Now, researchers from the University of Cambridge have developed a groundbreaking tool to predict and map these condensates across the entire human proteome – the complete set of proteins in human cells. Their work, published in Nature Communications, introduces the Protein Condensate Atlas, a comprehensive guide to the droplet-forming ...
4 dni temu · Using these methods, Regev’s team have discovered cells they did not know existed and play important roles in healthy tissues or diseases, including different cancers, Alzheimer’s disease, cystic fibrosis, and COVID-19. They were also the first to use single-cell methods to characterise solid tumours and have applied them to better ...
