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  1. 31 lip 2015 · MEKP is a potentially lethal industrial chemical. Acute poisoning can occur due to accidental or intentional ingestion. Ingestion can affect multiple organ systems, leading to short and long term morbidity.

  2. 7 sty 2022 · The main symptoms of oral MEKP poisoning include three aspects. The first symptom is corrosion of the digestive tract due to the corrosive effects of MEKP. The second symptom is that MEKP causes abnormal heart, liver and kidney function because of metabolic abnormalities in the body.

  3. According to the authors, the exposure to MEK did not produce any conclusive, consistently interpretable effect of chemical treatment. In contrast, ethanol ingestion produced significant decrements on every performance test except memory scanning.

  4. 17 gru 2020 · But the role of free radical scavengers, particularly NAC, vitamin E, and vitamin C in treating MEKP intoxication is noteworthy. A favorable outcome was documented when both oral and intravenous NAC was given in the first 24 hours.

  5. 31 lip 2015 · Reversible acute kidney injury (AKI) has been reported in almost a third of published case studies. This is mainly attributed to rhabdomyolysis and myoglobinuria [ 14 ]. MEKP can be aspirated resulting in proximal airway edema and obstruction, pneumonitis or acute respiratory distress syndrome [ 15 ].

  6. Ocular toxicities of MEK inhibitors and other targeted therapies. ABSTRACT. Many classes of anticancer therapy, including chemotherapeutic agents, hormonal and molecular targeted treatments, can produce ocular toxicity.

  7. 21 lis 2022 · Exposure to MEK may cause dryness, erythema, dermatitis, defatting of the skin and paraesthesia. Prolonged exposure may result in systemic toxicity.

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