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24 gru 2022 · Map distance tells the expected number of crossovers between two loci and can be used as a proxy of recombination; the longer the map distance the higher the recombination frequency.
By finding recombination frequencies for many gene pairs, we can make linkage maps that show the order and relative distances of the genes on the chromosome.
Calculate the map distance between loci given the phenotypes of offspring or predict phenotypes of offspring given the recombination frequency between loci. Use the distance to construct genetic maps based on data from two-point or three-point testcrosses.
A genetic map shows the map distance, in cM, that separates any two loci, and the position of these loci relative to all other mapped loci. The genetic map distance is roughly proportional to the physical distance, i.e., the amount of DNA between two loci.
31 paź 2023 · Linked genes can become unlinked during recombination; the probability of genes separating depends on their distance from each other.
Analyzing the number of offspring of each phenotype will allow us to determine the order of the genes on the chromosome and the map distances between them. The first thing to do in solving a three-factor cross is to count the number of phenotypes seen in the offspring.
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