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21 maj 2024 · Irregular Z-line, defined as < 1 cm segment of columnar mucosa in distal esophagus, is commonly encountered and frequently biopsied. Consensus guidelines recommend against biopsies of irregular z-line due to low risk of progression to esophageal cancer (EAC).
28 lut 2018 · An irregular Z line is characterized by < 1 cm columnar tongues that extend proximal to the gastroesophageal junction, a finding that has been reported in approximately 10–15% of the population undergoing upper endoscopy [1, 2].
Barrett's oesophagus should be endoscopically distinguished from an irregular Z-line, whereby the squamocolumnar junction appears with tongues of columnar epithelium shorter than 1 cm and with no confluent columnar-lined segment.
23 maj 2021 · Barrett’s esophagus (BE) is a known risk factor for esophageal adenocarcinoma (EAC) and consensus guidelines recommend a standardized approach to endoscopic screening and surveillance. Segments less than one centimeter are often described as an irregular Z line.
In pts with a normal SCJ, surveillance endoscopy was recommended in 81% of pts with IM on histology and 19% in individuals without IM. Similarly, in pts with an irregular Z-line, surveillance endoscopy was recommended in 82% and 24% of cases, respectively.
For patients with an irregular Z-line/columnar-lined esophagus of <1cm, no routine biopsies or endoscopic sur-veillance is advised. For BE ≥1cm and <3cm, BE surveillance should be repeated every 5 years. For BE 3cm and <10cm, the interval for. ≥. endoscopic surveillance should be 3 years.
8 sie 2022 · Endoscopic photograph of an irregular Z line. Note the relatively small displacement from the top of the gastric folds to the most proximal extent of the Z line. Figure 2. Hematoxylin and eosin staining of endoscopic biopsy of the irregular Z line, demonstrating intestinal metaplasia with goblet cells. Courtesy of John Goldblum, MD.
