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Aspirin is classified as a non-selective cyclooxygenase (COX) inhibitor 11,14 and is available in many doses and forms, including chewable tablets, suppositories, extended release formulations, and others 19.
- Flufenamic Acid
Imming P, Sinning C, Meyer A: Drugs, their targets and the...
- Benziodarone
Acetylsalicylic acid: The therapeutic efficacy of...
- Chloroxylenol
Glucuronic acid + Sulfuric acid; Route of elimination. The...
- H3N2
Indication Contraindications & Blackbox Warnings...
- Povidone-iodine
Generic Name Povidone-iodine DrugBank Accession Number...
- Flufenamic Acid
5 lip 2023 · This activity outlines the indications, mechanism of action, methods of administration, important adverse effects, contraindications, and monitoring, of salicylic acid, so providers can direct patient therapy in treating indicated conditions as part of the interprofessional team.
9 mar 2017 · The figure illustrates inhibition of platelet prostanoid production by aspirin and its functional and clinical consequences. The lines of evidence supporting the protective effects of aspirin are summarized below each panel.
Aspirin acts as an acetylating agent where an acetyl group is covalently attached to a serine residue in the active site of the COX enzyme. This makes aspirin different from other NSAIDs (such as diclofenac and ibuprofen), which are reversible inhibitors; aspirin creates an allosteric change in the structure of the COX enzyme.
17 lis 2011 · Antiplatelet drugs are classified on the basis of their site of action, that is, drugs that inhibit (i) platelet adhesion, (ii) platelet activation, (iii) platelet aggregation, and (iv) platelet-mediated links with inflammation . Aspirin belongs to the group of drugs that inhibit platelet activation.
Among 11 000 patients with a prior stroke or TIA, aspirin therapy was associated with an event rate of 18.4% compared with a rate of 22.2% in control subjects (3-year decrease in absolute event rate of 38 events per 1000 patients).
1 sty 2019 · Fig. 50.1. Arachidonic acid metabolism and mechanism of action of aspirin. Arachidonic acid, a 20-carbon fatty acid containing four double bonds, is liberated from the sn2 position in membrane phospholipids by several phospholipases, which are activated by diverse stimuli.
