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By finding recombination frequencies for many gene pairs, we can make linkage maps that show the order and relative distances of the genes on the chromosome.
Calculate the map distance between loci given the phenotypes of offspring or predict phenotypes of offspring given the recombination frequency between loci. Use the distance to construct genetic maps based on data from two-point or three-point testcrosses.
A genetic map shows the map distance, in cM, that separates any two loci, and the position of these loci relative to all other mapped loci. The genetic map distance is roughly proportional to the physical distance, i.e., the amount of DNA between two loci.
31 mar 2019 · Gene map distance: Gene map distance is the distance between points on a chromosome which can be estimated by counting the number of crossovers between them. Therefore, the distance between two points on the genetic map of a chromosome is the average number of crossovers between them.
Analyzing the number of offspring of each phenotype will allow us to determine the order of the genes on the chromosome and the map distances between them. The first thing to do in solving a three-factor cross is to count the number of phenotypes seen in the offspring.
Map distances are always calculated for one pair of loci at a time. However, by combining the results of multiple pairwise calculations, a genetic map of many loci on a chromosome can be produced (Figure 10-3). A genetic map shows the map distance, in cM, that separates any two loci, and the position of these loci relative to all other mapped ...
