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23 maj 2021 · Introduction. Barrett’s esophagus (BE) is a known risk factor for esophageal adenocarcinoma (EAC) and consensus guidelines recommend a standardized approach to endoscopic screening and surveillance. Segments less than one centimeter are often described as an irregular Z line.
Conclusions: The yield of biopsy at an “irregular z-line” is low. In addition, the risk of cancer in patients with this endoscopic finding and specialized intestinal metaplasia (even with dysplasia) is unknown.
3 lis 2022 · The Z line in the esophagus is the term for a faint zig-zag impression at the gastro-esophageal junction that demarcates the transition between the stratified squamous epithelium in the esophagus and the intestinal epithelium of the gastric cardia (the squamocolumnar junction).
In order to determine which endoscopic alterations that can be attributed to a previous history of gastroesophageal reflux, three different endoscopic definitions of columnar-lined esophagus (CLE) were used: (1) ZAP I, An irregular Z-line with a suspicion of tongue-like protrusions; (2) ZAP II/III, Distinct, obvious tongues of metaplastic ...
In BE, the squamous epithelium of the distal esophagus is replaced by columnar epithelium, thus displacing the squamocolumnar junction, also called the Z- line, orally, and giving rise to a columnar lined esophagus (CLE). In BE, there is an increased risk of developing esopha- geal adenocarcinoma (EAC) [2].
There is no accepted classification system for the endoscopic description of the squamocolumnar mucosal junction, the so-called “Z-line.” Furthermore, no clear definition of the normal Z-line exists. A classification of the Z-line appearance has been proposed: the ZAP classification.
28 lut 2018 · The Z line demarcates the squamocolumnar junction (SCJ), the transition from the squamous esophageal mucosa to the columnar mucosa lining the stomach, or in cases of Barrett’s esophagus, between the squamous and intestinalized columnar epithelium of the metaplastic segment.
