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AC-29 - DNA topoisomerase I (topo I)-like. 1) Prominent fine speckled AC-4 type nuclear staining in interphase cells. 2) Consistent strong fine speckled staining of condensed chromatin in mitotic cells.
5 sty 2022 · Second, the nuclear dense fine-speckled (AC-2) and Topo I-like (AC-29) patterns are realigned closer to the nuclear homogeneous pattern (AC-1) to highlight their similarities in staining of both interphase nuclei and mitotic condensed chromatin.
Speckled pattern distributed throughout the interphase nucleus with characteristic heterogeneity in the size, brightness and distribution of the speckles. Throughout the interphase nucleus, there are some denser and looser areas of speckles (very characteristic feature).
level reportable patterns. The six competent -level reportable nuclear patterns include homogeneous (AC - 1), speckled (AC -2, 4, 5), dense fine speckled (AC -2), centromere (AC -3), discrete nuclear dots (AC -6,7), and nucleolar (AC-8,9,10). Five competent-level reportable cytoplasmic patterns are fibrillar (AC-15, 16, 17),
23 lis 2020 · The highest scores for clinical relevance were obtained for the centromere (AC-3) and homogeneous (AC-1) pattern, followed by the nuclear speckled (AC-2,4,5) and cytoplasmic reticular (AC-21) patterns.
17 sty 2019 · Sjögren syndrome: common ANA pattern is speckled; less commonly homogenous. Related Content. Scleroderma or systemic sclerosis: ANA pattern is most commonly speckled, followed by centromeric...
5 sty 2022 · The International Consensus on ANA Patterns (ICAP) classifies 30 relevant patterns (AC-0 to AC-29). AC-4 (fine speckled nuclear pattern) is associated to anti-SS-A/Ro, anti-SS-B/La, and several...
