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12 cze 2024 · Reports indicate CVD events in up to 7.5% of patients with MM, with a median overall survival of 47.6 months observed in phase 3 clinical trials [ 14 ]. However, real-world evidence regarding the patterns of these events among large patient populations and long-term MM survivors is lacking.
- Multiple myeloma: signaling pathways and targeted therapy
Multiple myeloma (MM) is the second most common...
- Multiple myeloma: signaling pathways and targeted therapy
27 cze 2024 · Multiple myeloma (MM) is a haematological lymphoid malignancy involving tumoural plasma cells and is usually characterized by the presence of a monoclonal immunoglobulin protein.
28 cze 2024 · Multiple myeloma (MM), the second most frequent hematologic malignancy, is characterized by expansion of monoclonal plasma cells in the bone marrow. Patients suffer from bone lesions, renal ...
2 dni temu · Multiple myeloma (MM) is the second most common hematological malignancy of plasma cells, characterized by osteolytic bone lesions, anemia, hypercalcemia, renal failure, and the accumulation of malignant plasma cells. The pathogenesis of MM involves the interaction between MM cells and the bone marrow microenvironment through soluble cytokines and cell adhesion molecules, which activate ...
19 cze 2024 · Multiple myeloma (MM) represents the second most common hematological malignancy, but its diagnosis can be significantly delayed since symptoms are not specific and, mainly in the older population, alternate diagnoses can mimic MM. Bone marrow biopsy (evaluating the amount of proliferating myeloma cells) remains an essential procedure, but sever...
27 cze 2024 · This PrimeView highlights the epidemiology, mechanisms, diagnosis, management and quality of life of patients with multiple myeloma.
4 dni temu · Multiple myeloma (MM) is the second most common malignant hematologic disease. Bone involvement is one of the most common symptoms of MM (the acronym CRAB describes the most common clinical signs: hypercalcemia, renal impairment, anemia, and bone disease). Therefore, substantial morbidity, physical impairment, compression fractures, pain, and ...
