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21 godz. temu · Metabolic gene function discovery platform GeneMAP identifies SLC25A48 as necessary for mitochondrial choline import. Nature Genetics , 2024; DOI: 10.1038/s41588-024-01827-2
1 dzień temu · The data fusion method presented here integrates multi-omics datasets for gene prioritisation, biomarker discovery, and pathway enrichment analysis by finding genes and proteins with significant ...
26 cze 2024 · Known as the protein folding problem, it was simple to state: Could they accurately predict the three-dimensional shape of a protein molecule from the barest of information — its one-dimensional molecular code? Proteins keep our cells and bodies alive and running.
5 dni temu · The team has now assessed exons as potential protein folding modules across 38 abundant and conserved protein families. Over generations, exons can shuffle randomly along the genome, leading to significant changes in genes and the creation of new proteins.
1 lip 2024 · There are five KEGG Mapper tools as summarized below. Reconstruct is the basic mapping tool used for linking KO annotation (K number assignment) data to KEGG pathway maps, BRITE hierarchies and tables, and KEGG modules.
1 lip 2024 · Protein transport can be facilitated by a variety of pathways including membrane trafficking, protein translocation, and endocytosis or exocytosis.
28 cze 2024 · The longest introns located in the 1 st tertile of all introns in the gene are significantly longer than the longest introns in the 2 nd or 3 rd tertile. By dividing the protein-coding genes into a group with the longest intron located in the 1 st tertile and a group with the longest intron in the 2 nd or 3 rd tertile, two approximately equally numerous groups will be created in all tested ...
