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19 godz. temu · To discover functions for "orphan" transporters and enzymes -- proteins with unknown substrates -- the researchers developed the GeneMAP discovery platform. They used datasets from two independent ...
19 godz. temu · GeneMAP discovery platform will help define functions for ‘orphan’ metabolic proteins. The combination of genomics and metabolism identified a long-sought mitochondrial choline transporter. A multidisciplinary research team has developed a discovery platform to probe the function of genes involved in metabolism — the sum of all life ...
19 godz. temu · Metabolic reactions play critical roles in nutrient absorption, energy production, waste disposal, and synthesis of cellular building blocks including proteins, lipids and nucleic acids. About 20% of protein-coding genes are dedicated to metabolism, including genes that code for small-molecule transporters and enzymes, Gamazon said.
3 godz. temu · Scientists develop platform to help define functions for 'orphan' metabolic proteins. New Delhi, July 8 (IANS) A team of US scientists on Monday announced the development of a discovery platform to probe the function of genes involved in metabolism. The scientists used the new platform, called 'GeneMAP' (Gene-Metabolite Association Prediction ...
3 dni temu · Gene mapping refers to the process of determining the location of genes on chromosomes. Today, the most efficient approach for gene mapping involves sequencing a genome and then using computer programs to analyze the sequence to identify the location of genes.
2 dni temu · Some genome maps reflect the location of big chromosomal regions. Other genome maps reflect the location of genes that encode proteins or places where the DNA spelling is different among people (known as genomic variants).
6 dni temu · Autoimmune disorders (ADs) are chronic conditions resulting from failure or breakdown of immunological tolerance, resulting in the host immune system attacking its cells or tissues. Recent studies report shared effects, mechanisms, and evolutionary origins among ADs; however, the possible factors connecting them are unknown. This study attempts to identify gene signatures commonly shared ...
