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19 cze 2024 · By preserving the locations of cells from in vivo recordings to their ex vivo positions, large multidimensional datasets that incorporate neurophysiology with single-cell sequencing...
8 lip 2024 · Single-cell multiomic analysis of the epigenome, transcriptome, and proteome allows for comprehensive characterization of the molecular circuitry that underpins cell identity and state. However, the holistic interpretation of such datasets presents a challenge given a paucity of approaches for systematic, joint evaluation of different modalities.
8 lip 2024 · Finally, we integrated this atlas with the previous single-cell chromatin accessibility dataset from 13 adult mouse tissues to delineate the developmental stage-specific gene regulatory programmes ...
4 dni temu · A physical map, as related to genomics, is a graphical representation of physical locations of landmarks or markers (such as genes, variants and other DNA sequences of interest) within a chromosome or genome. A complete genome sequence is one type of physical map.
4 dni temu · Mapping refers to the process of determining the relative locations of landmarks or markers (such as genes, variants and other DNA sequences of interest) within a chromosome or genome.
1 dzień temu · The metadata in the Allen Brain Cell Atlas, though, seems to use a parcellation index rather than the anatomical ontology IDs used in other datasets. For example, the “Entorhinal area, lateral part, layer 1” has a parcellation index of 1109.
19 cze 2024 · Here, we generate single-cell RNA-seq maps of neuroblastoma cell lines, patient-derived xenograft models (PDX), and a genetically engineered mouse model (GEMM).
