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3 dni temu · Distance matrices - PLINK 2.0. Quick index search. Sample-distance and similarity matrices. Relationship/covariance. --make-rel ['cov'] ['meanimpute'] [ {square | square0 | triangle}] [ {zs | bin | bin4}] --make-rel is the primary interface to PLINK's genetic relationship matrix and covariance matrix calculator.
27 cze 2024 · The development and application of molecular markers, such as single-nucleotide polymorphisms (SNPs), have enabled the integration of functionally validated genetic markers with the genomic best linear unbiased prediction (GBLUP) method for molecular marker-assisted selection of breeding values.
30 cze 2024 · Estimate genetic maps. Description. Uses a hidden Markov model to re-estimate the genetic map for an experimental cross, with possible allowance for genotyping errors. Usage. est_map( cross, error_prob = 0.0001, map_function = c("haldane", "kosambi", "c-f", "morgan"), lowmem = FALSE, maxit = 10000, tol = 0.000001, quiet = TRUE, save_rf = FALSE,
4 dni temu · A genetic map (also called a linkage map) shows the relative location of genetic markers (reflecting sites of genomic variants) on a chromosome. A genetic map is based on the concept of genetic linkage: the closer two markers are to each other on a chromosome, the greater the probability that they will be inherited together.
17 cze 2024 · The Gene Ontology (GO) knowledgebase is the world’s largest source of information on the functions of genes. This knowledge is both human-readable and machine-readable, and is a foundation for computational analysis of large-scale molecular biology and genetics experiments in biomedical research.
17 cze 2024 · The shortest_paths method of Graph computes the shortest paths using the Floyd-Warshall algorithm. For example, the graph above has the following distances matrix: [10] 0. After running the shortest_paths command, paths from source (s) to destination (t) can be extracted with the path method.
6 dni temu · Crossing over is an extremely important mechanism for increasing genetic diversity in animals. The frequency with which crossing over occurs between any two linked genes is proportional to the distance between them.
