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24 gru 2022 · Map distance is one of the key measures in genetics and indicates the expected number of crossovers between two loci.
24 maj 2021 · This tutorial provides guidelines for interpreting single-cell transcriptomic maps to identify cell types, states and other biologically relevant patterns.
8 lip 2024 · Panpipes also includes four workflows dedicated to spatial transcriptomics, including: “Ingestion,” “Preprocessing,” “Clustering,” and “Deconvolution” (Fig. 1).The unifying aim across these workflows is to guide the user through the key decision-making steps of the analytical process and to gather all the data necessary to annotate cell types and states.
5 kwi 2024 · To visualize the geometry of all genes, we convert pairwise gene–gene Wasserstein distances into gene–gene affinities and use diffusion map to get a low-dimensional representation of genes.
GI maps give two distinct types of information: clustering of genes by similarities of their profile of GIs informs assignment of genes to complexes, pathways, or processes; specific GIs reveal functional connections between gene pairs (Figure 1A). Here, we first describe the structure and insights gained from gene clustering and then discuss ...
A genetic map (or recombination map) is a representation of the linear order of genes (or loci), and their relative distances determined by crossover frequency, along a chromosome. The fact that such linear maps can be constructed supports the concept of genes being arranged in a fixed, linear order along a single duplex of DNA for each chromosome.
7 lip 2022 · Heatmap displays log 2 -fold changes in expression of highly expressed transposable element metagenes (columns) for genetic perturbations (rows) in K562 cells (day 8) Perturb-seq. Genetic perturbations and genes are ordered by average linkage hierarchical clustering with a Euclidean distance metric.
