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24 maj 2021 · This tutorial provides guidelines for interpreting single-cell transcriptomic maps to identify cell types, states and other biologically relevant patterns.
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In linkage maps, you may see distances expressed as centimorgans or map units rather than recombination frequencies. Luckily, there's a direct relationship among these values: a 1 % recombination frequency is equivalent to 1 centimorgan or 1 map unit.
24 gru 2022 · Map distance is one of the key measures in genetics and indicates the expected number of crossovers between two loci.
19 cze 2019 · Single‐cell RNA ‐seq has enabled gene expression to be studied at an unprecedented resolution. The promise of this technology is attracting a growing user base for single‐cell analysis methods.
The process of labeling groups of cells in your data based on known (or sometimes unknown) cellular phenotypes is called “cell annotation”. Whereas there are many ways to annotate your cells (e.g. based on batch, disease, sex and more), in this notebook we will focus on the annotation of “cell types”.
A genetic map (or recombination map) is a representation of the linear order of genes (or loci), and their relative distances determined by crossover frequency, along a chromosome. The fact that such linear maps can be constructed supports the concept of genes being arranged in a fixed, linear order along a single duplex of DNA for each chromosome.
Explain the basis of sequence tagged site ( STS) mapping, and list the various DNA sequences that can be used as STSs. Describe how radiation hybrids and clone libraries are used in STS mapping. The next two chapters describe the techniques and strategies used to obtain genome sequences.
