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21 wrz 2021 · Therefore, we created a whole-body map of sex differences in gene co-expression, based on gene co-expression and expand on the overarching sex-biased pathways.
19 lut 2018 · Here we review the evidence that gender identity and related socially defined gender constructs are influenced in part by innate factors including genes. Based on the data reviewed, we hypothesize that gender identity is a multifactorial complex trait with a heritable polygenic component.
27 gru 2019 · Our findings suggest a new avenue for investigation of genes involved in estrogen signaling pathways related to sexually dimorphic brain development and their relationship to gender dysphoria.
10 mar 2020 · By including gender in genomic somatic research, researchers can expand our understanding of the genome and the factors that modify its expression, ensuring that gender inequities are not ...
9 mar 2022 · We can analyze genetic data to demonstrate how genes do not map onto socially defined racial and ethnic groups, and we can make the point that relatively little variance is explained by studies focusing exclusively on genetic contributions to complex traits.
5 sie 2020 · The review of the literature suggests that there is a disparity between the brains of those who identify differently to their assigned gender at birth, highlighting a multifactorial underpinning of the gender identity.
26 kwi 2018 · Using a graph-based approach, we mapped a cell-state landscape that describes axis patterning, germ layer formation, and organogenesis. We tested how clonally related cells traverse this landscape by developing a transposon-based barcoding approach (TracerSeq) for reconstructing single-cell lineage histories.
