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There are 241.70 miles from Saint Louis to Louisville in east direction and 260 miles (418.43 kilometers) by car, following the I-64 E route. Saint Louis and Louisville are 3 hours 55 mins far apart, if you drive non-stop .
Travelmath helps you find driving distances based on actual directions for your road trip. You can get the distance between cities, airports, states, countries, or zip codes to figure out the best route to travel to your destination.
Calculate the mileage and driving time for your trips with MapQuest. Plan your routes, avoid traffic and find nearby hotels and restaurants.
How far is it to drive from Saint Louis, Missouri to Louisville, Kentucky? View a map with the driving distance between Saint Louis, MO and Louisville, KY to calculate your road trip mileage.
Use the road trip planner to drive from St. Louis to Louisville using the best route and find places to stop.
Distance Calculator Between Cities for Precise Driving Distances. Efficiently find the distance between cities, including driving distances, estimated travel times, and detailed route maps for any journey in the USA, from cross-country adventures to short drives.
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