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The Fugates, commonly known as the "Blue Fugates" or the "Blue People of Kentucky", are an ancestral family living in the hills of Kentucky starting in the 19th century, where they are known for having a genetic trait that led to the blood disorder methemoglobinemia, causing the skin to appear blue.
6 mar 2023 · A mutated gene causes their bodies to build up a rare form of hemoglobin called methemoglobin that can't bond with oxygen. If enough blood is "infected" with this faulty type of hemoglobin, it changes from red to an almost purple-ish dark blue. For the Fugates, family members expressed the gene to varying degrees.
5 sie 2023 · Dr. Madison Cawein, in the 1960s, identified the cause of the blue skin as methemoglobinemia, resulting from an enzyme deficiency. He used Methylene Blue to treat and revert the blue skin to a normal tone.
21 mar 2023 · Known as the blue people of Kentucky, the Fugate family settled in Appalachia in 1820 and became famous for a recessive gene that made their skin bright blue. For 197 years, the Fugate family has remained sealed off from the outside world as they've passed their blue skin through the generations.
21 lut 2012 · The Fugate progeny had a genetic condition called methemoglobinemia, which was passed down through a recessive gene and blossomed through intermarriage.
Deep in the woods of Kentucky, a fiercely private family gave birth to blue-skinned children since the 1800s. The color of their skin was so shocking for normal people to see, that they chose to stay hidden away from the rest of society in their small community.
12 sie 2022 · They carried a rare blood disorder called methemoglobinemia, which affects how the blood carries and releases oxygen. In the Fugates, it didn't harm their physical health (the family was noted...
