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28 lut 2018 · An irregular Z line is characterized by < 1 cm columnar tongues that extend proximal to the gastroesophageal junction, a finding that has been reported in approximately 10–15% of the population undergoing upper endoscopy [1, 2].
21 maj 2024 · Consensus guidelines recommend against biopsies of irregular z-line due to low risk of progression to esophageal cancer (EAC). Despite this, presence of irregular Z-line with or without intestinal metaplasia (IM), dysplasia or EAC is encountered in practice and clinical significance is unclear.
Conclusions: The yield of biopsy at an “irregular z-line” is low. In addition, the risk of cancer in patients with this endoscopic finding and specialized intestinal metaplasia (even with dysplasia) is unknown.
In order to determine which endoscopic alterations that can be attributed to a previous history of gastroesophageal reflux, three different endoscopic definitions of columnar-lined esophagus (CLE) were used: (1) ZAP I, An irregular Z-line with a suspicion of tongue-like protrusions; (2) ZAP II/III, Distinct, obvious tongues of metaplastic ...
Barrett's oesophagus should be endoscopically distinguished from an irregular Z-line, whereby the squamocolumnar junction appears with tongues of columnar epithelium shorter than 1 cm and with no confluent columnar-lined segment.
center cohort study, we found that patients with irregular Z line do not develop HGD or esophageal cancer within 5 years after index endoscopy. Keywords: Cancer Tumorigenesis. Detection; Screening; Population;
23 maj 2021 · Segments less than one centimeter are often described as an irregular Z line. These segments are low risk lesions and are frequently encountered during endoscopy for indications other than BE. Biopsy is not recommended as this leads to unnecessary procedures, patient anxiety and additional expenditures.
