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19 lip 2021 · Three major forms of DNA are double stranded and connected by interactions between complementary base pairs. These are terms A-form, B-form,and Z-form DNA.
27 sty 2022 · We consider double‐stranded B‐DNA triplets with a charged backbone (d(DNA) −4) and a backbone neutralized by either H + (d(DNA) H+) or Na + (d(DNA) Na+) counterions. All 32 possible sequences of duplex DNA triplets were examined, considering Watson–Crick base pairing (Figure 1 b).
13 lis 2021 · With simple steric considerations and geometric constraints based on a few structural parameters at the base (propeller twist) and basepair (roll and slide) level, a set of rules to describe the 3D structure of B-DNA from sequence was proposed (Calladine 1982; Fratini et al. 1982).
A base pair (bp) is a fundamental unit of double-stranded nucleic acids consisting of two nucleobases bound to each other by hydrogen bonds. They form the building blocks of the DNA double helix and contribute to the folded structure of both DNA and RNA.
Canonical B-DNA is a double helix made of two antiparallel strands that are held together via hydrogen bonding in the A•T and G•C base pairs (fig. 1). One helical turn of B-DNA contains about 10.5 base pairs that are buried inside the helix and are almost perpendicular to the helical axis.
We have computationally investigated the structure and stability of B-DNA. To this end, we have analyzed the bonding in a series of 47 stacks consisting of two base pairs, in which the base pairs cover the full range of natural Watson–Crick pairs, mismatched pairs, and artificial DNA base pairs.
13 lis 2021 · Sequence-dependent structural properties of B-DNA: what have we learned in 40 years? Review. Published: 13 November 2021. Volume 13, pages 995–1005, (2021) Cite this article. Download PDF. Gabriela da Rosa, Leandro Grille, Victoria Calzada, Katya Ahmad, Juan Pablo Arcon, Federica Battistini, Genís Bayarri, Thomas Bishop, Paolo Carloni,
