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1 lis 2017 · IL-8 plays key roles in the immunobiology of human malignancies and resistance to treatments. Circulating IL-8 concentration reflects tumor burden. Change in serum IL-8 is a biomarker to follow immunotherapy with checkpoint inhibitors.
- Prognostic impact of Interleukin-8 levels in lung cancer: A meta ...
High interleukin-8 levels are related with poor prognosis in...
- Interleukin-8: A chemokine at the intersection of cancer plasticity ...
IL-8 has been shown to influence the biology of numerous...
- Prognostic impact of Interleukin-8 levels in lung cancer: A meta ...
11 maj 2020 · Interleukin-8, produced by intratumoral and circulating myeloid cells, correlates with an immunosuppressive myeloid-enriched tumor microenvironment and adverse cancer prognosis.
1 sie 2024 · High interleukin-8 levels are related with poor prognosis in several solid cancers. This meta -analysis confirmed the prognostic impact of circulating baseline IL-8 levels in advanced lung cancer, especially, in patients treated with chemotherapy and/or immunotherapy.
3 lis 2008 · Increased expression of IL-8 and/or its receptors has been characterized in cancer cells, endothelial cells, infiltrating neutrophils, and tumor-associated macrophages, suggesting that IL-8 may function as a significant regulatory factor within the tumor microenvironment.
1 mar 2021 · IL-8 has been shown to influence the biology of numerous types of cancer, including melanoma, prostate, colon, pancreatic, breast, and lung (Cheng et al., 2019). The overarching functions of the chemokine within these cancers can be broadly divided into two categories, direct and indirect effects.
11 maj 2020 · Here, using a large-scale retrospective analysis, we show that elevated baseline serum IL-8 levels are associated with poor outcome in patients (n = 1,344) with advanced cancers treated with...
11 maj 2020 · Here we analyzed circulating pIL-8 and IL8 gene expression in peripheral blood mononuclear cells and tumors of patients treated with atezolizumab (anti-PD-L1 monoclonal antibody) from multiple...
