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Diagnosis of juvenile dermatomyositis is suspected clinically in a child presenting with the classic skin signs of heliotrope rash, Gottron papules/sign, and myositis (Bohan Peters diagnostic criteria).
Anti-NXP-2 is found in younger children and is associated with calcinosis; anti-TIF-1γ+ juvenile dermatomyositis has a longer disease course. The diagnostic rash—involving the eyelids, hands, knees, face, and upper chest—is the most persistent symptom and is associated with microvascular compromise, reflected by loss of nailfold ...
16 sty 2023 · The juvenile form is associated with multisystemic vasculitis and a high frequency of calcinosis, Gottron papules, symmetrical proximal muscle weakness, and a heliotrope rash. However, unlike the adult form, it does not have an increased risk of malignancy.
3 maj 2020 · Juvenile dermatomyositis is the most common type of juvenile idiopathic inflammatory myopathy mainly affecting the skin and proximal muscles.
16 kwi 2024 · Children with juvenile dermatomyositis often have a skin rash. It may start as reddish or purplish cheeks and eyelids. Your child may have puffy eyelids that get misdiagnosed as allergies. Over time, your child may develop inflamed patches of dry skin or bumps over their knuckles, knees or elbows.
Juvenile dermatomyositis (JDM) is a rare heterogeneous immune-medicated condition with characteristic skin rashes, muscle weakness, vasculopathy, and other organ involvement.
Juvenile dermatomyositis (JDM) is a rare disease within the group of paediatric rheumatic diseases (PRDs) and can lead to significant morbidity. Evidence-based guidelines are sparse and management is mostly based on physicians' experience. Consequently, treatment regimens differ throughout Europe.
